Most played cards in Smallpox:

1 Decks
Dark Ritual
4 copies - 4 average
Wasteland
4 copies - 4 average
Liliana of the Veil
4 copies - 4 average
Smallpox
4 copies - 4 average
Leyline of the Void
4 copies - 4 average
Urborg, Tomb of Yawgmoth
4 copies - 4 average
Thoughtseize
4 copies - 4 average
Mishra's Factory
4 copies - 4 average
Ensnaring Bridge
3 copies - 3 average
Orcish Bowmasters
3 copies - 3 average
Snow-Covered Swamp
3 copies - 3 average
Sheoldred's Edict
2 copies - 2 average
Opposition Agent
2 copies - 2 average
Torpor Orb
2 copies - 2 average
Chains of Mephistopheles
2 copies - 2 average
Karn, the Great Creator
2 copies - 2 average
Innocent Blood
2 copies - 2 average
Castle Locthwain
2 copies - 2 average
Urza's Saga
2 copies - 2 average
Pithing Needle
1 copies - 1 average